Matt Henke

The Henke Lab takes a chemical-first approach 1) to gain molecular and mechanistic understanding behind microbiome associations to health and disease and 2) to develop chemical tools that can be used to re-engineer host phenotypes or microbial community structure.

We are primarily interested in three area of research:
1) Cataloguing the functional chemical dark matter present in the human metabolome.
2) Exploring how microbial competition manifests in the gut and how this effects human health.
3) Identifying microbial molecular effectors driving human immune alterations.